A Rapid Sample Pretreatment Protocol: Improved Sensitivity in the Detection of a Low-abundant Serum Biomarker for Prostate Cancer

Mun'delanji VESTERGAARD1) and Eiichi TAMIYA2)

1) School of Material Science, Japan Advanced Institute of Science and Technology 2) Department of Applied Physics, Osaka University

(Received August 1, 2007) (Accepted October 23, 2007)

We have developed a rapid immunoglobulin G (IgG) and a human serum albumin (HSA) depletion protocol. We depleted both HSA and IgG (> 97%) separately, and in a single procedure. The method is specific and reproducible (RSD <>

Anal. Sci., Vol. 23, p.1443, (2007)